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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T15727 | Sonidegib diphosphate | NVP-LDE 225 diphosphate,Erismodegib diphosphate,LDE225 diphosphate | Smo |
Sonidegib diphosphate (LDE225 diphosphate) is an effective and selective Smo antagonist (IC50: 1.3 nM and 2.5 nM for mouse and human Smo in a binding assay, respectively). | |||
T1926 | Sonidegib | Erismodegib,NVP-LDE225,LDE225 | Hedgehog/Smoothened , Smo |
Sonidegib (Erismodegib), a Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively. |